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On the other hand, mast cells could also be detrimental to tumour growth by secreting several cytokines and proteolytic enzymes participating in inducing apoptosis of the malignant cells, such as IL-4 [ 13].
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On the other hand, the mast must be sufficiently tall that it doesn't get buried by snow," explained Dr David Jones, who leads the technical development on Project Javelin.
Put their shoulders to the wheel, all hands to the mast, and all shoot from the same trench, to mix my metaphors".
On the other hand, in some circumstances, mast cells exhibit anti-inflammatory and immunosuppressive functions [ 24, 25], suggesting that mast cells have both positive and negative impacts on immune responses.
On the other hand, the role of mast cells in chronic inflammation and other long-term tissue changes that are observed in some IgE associated diseases, including asthma, still debated [ 10].
Although the crew who had climbed into the rigging threatened the Malagasy from the fore-mast with hand grenades, "only those that reached the safety of the barricaded [gunroom] ... escaped a brutal death".
"Who's nervous?" A dozen or so others, including this reporter, barely managed to raise their hands to half-mast.
On the other hand, the relative paucity of mast cells in the functional layer may contribute to the immune tolerance of the gestational endometrium to the implantation of the blastocyst.
Their cookbook details a chocolate-making process that involves cacao beans shipped to Brooklyn from all over the world, roasted and ground using techniques perfected by the Mast's own hands.
Not John Nanci, but the Masts had no hand in its design.
The only way to get the several-hundred-pound mainsail up the mast was to hand-crank it using a complex grinding system.
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