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On the other hand, deletion of the respective prostaglandin receptors leads to reduced carcinogenesis and enhanced antitumor immunity [6].
On the other hand, deletion of the yeast PME-1 gene did not result in an observable cellular phenotype, even though PP2A methylation levels were enhanced [26].
On the other hand, deletion of either the Ig- or the TSP-domains of Unc5D abolished FLRT3 interaction in cell surface binding experiments (Figure 1F), revealing that both domains are required for efficient FLRT3 binding.
On the other hand, deletion of ser-4 significantly suppressed aldicarb hypersensitivity of the eat-6 ad467 eat-6 ad467ggesting that SER-4 activity is required for the increased aldicarb sensitivity of the eat-6 mutant.
On the other hand, deletion or duplication on chromosome 1, 11 or 22, may lead to abnormal expression of genes which are all involved in cell lipid metabolism, including PLD5, LRP5L and AMBRA1.
On the other hand, deletion of PHB1 or PHB2 (the tumor suppression protein prohibitin and its homolog) displayed no detectable phenotype, but was found to be synthetically lethal when any of the genes MDM12, MDM10 or MMM1 on the right side of the partition were mutated [20].
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On the other hand, deletions at the Notch1 locus were found in the respective lymphomas but not in premalignant cells (Fig. 6A, B).
On the other hand, deletions of levQ almost always led to drastic reductions in the activity of the fruA/levD promoters, similar to levels observed following deletion of levR.
On the other hand, deletions in tcdC are frequently present in toxinogenic isolates.
On the other hand, after deletion of the ackA pta pathway, cell growth is accelerated at acidic pH and the activity of the poxB gene product is enhanced (Dittrich et al. 2005).
On the other hand, the deletion of phosphotransacetylase strongly inhibited the bioprocess, suggesting that an adequate flux of acetyl-CoA and the connection of the phosphoenolpyruvate glyoxylate cycle together with the acetate metabolism are crucial for the biotransformation.
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