Currently, all annotations of spatial gene expression is hand curated by domain experts.
Information was obtained from GO annotations and hand curated with input from MGI and PubMed sources.
Other hand curated comprehensive databases for 'for storing, classifying, searching, predicting, and designing potent peptides against pathogenic bacteria, viruses, fungi, parasites, and cancer cells' do not enjoy the automation and vastness of available data elucidated in the SCALPEL methodology.
For example, a hand curated list of structures could be created on PDBWiki and used in a custom report.
On the other hand, curated contigs that may encode enzymes for the oxidative processing of the tetracyclic intermediate ent-kaurene to gibberellin A4 are present in the transcriptome at low sequence coverage (Additional file 1: Table S12).
Wilson [ 36] compared phonetic algorithms and hand curated mappings on a genealogical database, finding the hand-curated mappings more appropriate for name matching.
For subsets of chemicals, structures have been hand curated and quality reviewed as part of the U.S. EPA DSSTox program (Richard et al. 2008).
For testing, we use three benchmarks, the difficult hand curated alignments by Mayr et al. (2007), the classification benchmark by Sierk and Pearson (2004) and the benchmark at the Fatcat server.
The two groups were then hand curated and merged back into the complete multiple alignment using the splicer merge command.
In recent, prior work, we hand curated a multidomain benchmark dataset and used it to evaluate the performance of currently used methods for pairwise homology prediction (Song et al., 2008).
Moreover sequence divergence is nearly as effective when computed on automatically defined ortholog sets as on hand curated ones.
