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We found that functional inhibition of endogenous RARα in breast cancer cells by using either RARα specific antagonists or a dominant negative RARα mutant hampers on one hand the RA-induced upregulation of neutral sphingomyelinase (nSMase -mediated CER synSMase -mediatedthe other hand the RA-induCER downregulation of synthesisne kinand 1, SK1, pivonal for S1P synthesis.
We've been hard at work testing (ok, eating) the best of the hampers on offer this year to bring you 12 fit for any foodie, whether you're an adventurous cook, a coffee addict or simply looking to take some of the effort out of Christmas afternoon.
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However, bad weather conditions were hampering on-going search efforts, authorities said.
Protesters quickly formed a blockade, hampered on one side by police boats.
Second, it hampers follow-on improvements by firms that implement an existing technology but build upon it as well.
The sun is shining and there is a Christmas hamper on the back seat of the car – one of 550 to be delivered in Salisbury this month.
When fully engaged in basketball competition, Khalid El-Amin resembles an overflowing laundry hamper on wash day.
Ms. Krueger's children must put laundry in a hamper on a specific weekday.
Stability of nanocomplexes is not hampered on pretreatment, thereby avoiding nuclease-mediated degradation.
Mobaasher, who went off a well-supported favourite, stayed on into fifth after getting badly hampered on the final circuit.
Today, Smith's bid to penetrate the blue heart of Surrey Heath is hampered on several counts.
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