Unfortunately, with model details come parameters, and most parameters are generally unknown, thereby hampering the possibility for obtaining quantitative predictions.
16 Historically, cytogenetics has been difficult to perform in WM cells due to their low proliferation rate, hampering the possibility of obtaining metaphases.
However, paradoxically these workarounds, designed to reduce the workload of users, also made the use of the system very specific to users' own contexts, thereby hampering the possibility of meaningful communication between interoperable systems being used in different contexts [ 55].
However, the small binding potential values would hamper the possibility of using this radioligand to assess AMPA receptor density or occupancy.
On the other hand, the presence of the polymer did not hampered the possibility to remote load a weak acid model molecule (5 6 -carboxyfluorescein) using a transmembrane pH gradient.
The main reasons for this are the following: Scientists and decision makers speak different languages and have different background knowledge, points of view, and priorities; these conditions hamper the possibility of an easy understanding of research results by decision makers [35].
The main reasons for this are the following: (a) Scientists and decision makers speak different languages and have different background knowledge, points of view, and priorities; these conditions hamper the possibility of an easy understanding of research results by decision makers [35].
In particular, despite the availability of the structure of CP29 obtained at near atomic resolution in 2011 (Pan et al., 2011), the mismatch in pigment content and spectroscopic properties between CP29 in solution and in the crystal has hampered the possibility to use the structure to interpret the experimental data.
This polarization is troubling for the future of American democracy, as it hampers the possibility of consensus-building.
Altogether, this complexity of circadian entrainment, even within a single organ, may hamper the possibility of defining a unique internal body time based on genome-wide expression profiles in one peripheral tissue, as this has been proposed [37], [38].
Studies conducted so far on tumor samples and normal tissues rely on the use of commercially and non-commercially available antibodies recognizing both α-enolase and MBP-1, this has hampered the possibility to clearly evaluate the relative expression of the two proteins by immunohistochemistry.
