Sentence examples for hampering the function of from inspiring English sources

Exact(1)

Alcohol affects membrane and lipid-raft function both directly and indirectly by modulating the proinflammatory cascade as well as antiviral pathways and intracellular lipid storage within the parenchymal liver cells and hampering the function of nonparenchymal liver cells through both lipid-raft dependent and –independent mechanisms.

Similar(59)

In particular, the bill does not stipulate whether metal parts required under the law can be removed without hampering the functioning of the weapon.

Thus these results show that variants found in single SCCs can be found at detectable levels in the muscle and, if pathogenic, hamper the function of the whole tissue.

To this aim, we decided to hamper the function of the TrkB receptor by siRNA and monitor the level of phosphorylation of Ret following RA-treatment of SH-SY5Y (Figure 4A, left panel) and LAN-5 cells (Figure 4A, right panel).

Finally, we demonstrate that mutations abolishing the membrane remodelling activity of the Pex11-Amph domain also hamper the function of full-length Pex11 in peroxisome fission in vivo.

We propose that while the number of spermatids produced at both temperatures is reduced, inefficient fertilization further hampers the function of spermatids produced at restrictive temperature.

For example, Paroxetine, a selective serotonin reuptake inhibitors often used to treat depression may hamper the function of vascular endothelial cells by impairing endothelial nitric oxide synthase, thus affecting arterial integrity leading to cardiovascular diseases [ 44].

The critical passage in Draghi's comments was this: "To the extent that the size of the sovereign premia hamper the functioning of the monetary policy transmission channels, they come within our mandate".

Such construction or evolution of a new module would not significantly hamper the functioning of the old modules, and are thus favorable both for engineering purposes and for evolution, which could be facilitated [31] by this module-level modification.

Finally, as the private sector appears to be an important provider of reproductive health services in the three countries studied, care should be taken to prevent the implementation of policies or regulations that significantly burden or hamper the functioning of the private sector lest national-level reproductive health indicators suffer as a result.

These pathological accumulations at the nuclear envelope cause severe alterations in nuclear morphology and organization, hampering the normal functions of cells and leading ultimately to premature aging phenotypes exhibited by affected patients [ 6].

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