Provincial barriers to trade hamper the efficient allocation of resources.
The existence of multiple ligand-binding sites and a lack of structural information have hampered the efficient screening of drugs capable of acting on GABAARs.
Carbon catabolite repression (CCR) will occur and hamper the efficient production of bio-products if E. coli strains are cultivated in a mixture of sugars containing some preferred sugar, such as glucose.
This hypothetic alternative processing is, however, likely to hamper the efficient polymerization of the pilin subunits, as shown by the fact that the intensity of the higher molecular weight Sfp1-polymers was lower in the ΔsipF mutant than it was in the WT strain (Figure 2).
Generally, the reporter gene expression from split-CreERT2 proteins was lower than that from the non-inducible forms of split-Cre (N+C; Fig. 2A, 4A), indicating lower recombination activity of split-CreERT2 compared to split-Cre in cell culture, which might hamper the efficient targeting of cells in living mice.
But even if Q is finite, several factors can hamper the efficient solution of the matrix exponential in Eq. (5).
However, early and accurate diagnosis of AD still remains a big challenge and the lack of reliable method for its early diagnosis hampers the efficient drug development seriously.
The lack of data on the burden of disease morbidity and mental health status in slums hampers the efficient allocation of health care initiatives and the provision of appropriate disease prevention services [ 9].
Moreover, the understanding of molecular processes involved in esophageal cancer is not complete, hampering the development of efficient diagnostics and therapy.
The challenge is to deliver this in an efficient and effective manner without hampering the creative vision and innovation of the scientists involved.
