Exact(3)
In this review, we go over major clinical trials conducted in SLE by analyzing any critical aspects related to study design, predefined endpoints and biological activity of novel compounds that may have hampered study outcome, despite the great effort of providing less toxic drugs within a targeted, pathogenic-based approach.
Scientific limitations have hampered study of these real-world conditions and impaired our understanding of exactly how air pollutants affect health.
The fact that the koniocellular layers of the macaque LGN are very thin and dispersed has hampered study of the functional properties of koniocellular regions in this species.
Similar(57)
Budget constraints, including the $10,000 to $20,000 a day it costs to rent a research vessel, have hampered studies.
Plk1 depletion by siRNA results in several early mitotic defects that have hampered studying the cytokinesis specific functions of Plk1 [31] [31].
These biases may have hampered studies in this area.
The lack of suitable research tools has hampered studies of the distribution and retention of BPs in tumour models.
In particular, the dogmatic belief that the blood-brain barrier excludes cross-talk between both systems hampered studies in this field for a long time.
The lack of a suitable cellular paradigm and/or animal models has hampered studies on mitochondrial biogenesis at the early stages of neurogenesis.
The difficulty of accurately assessing caloric intake and energy expenditure [ 3] has hampered studies relating to energy restriction, caloric balance, and caloric intake in both epidemiology and clinical nutrition.
Comparative mitochondrial genomics of arbuscular mycorrhizal fungi (AMF) provide new avenues to overcome long-lasting obstacles that have hampered studies aimed at understanding the community structure, diversity, and evolution of these multinucleated and genetically polymorphic organisms.
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