It is fragile, heavyweight, and a little high resistive, hampering its application in large-area solar cell modules.
However, its poor water solubility hampers its application in pharmaceutical fields.
However, the feature importance score generated by machine learning methods is not statistically interpretable, which hampers its application in practice like medical diagnosis.
However the major challenges of UMDO, namely the computational complexity and organizational complexity caused by both time-consuming disciplinary analysis models and UMDO algorithms, still greatly hamper its application in aerospace engineering.
Bioremediation is envisaged as an important way to abate groundwater contamination, but the need for chemical addition and limited bioavailability of electron donors/acceptors or contaminants hamper its application.
Gastroscopy appears to be the most accurate method for the detection of gastric lesions; however, patient discomfort, risk of cross-infection, the high cost of screening, and the lack of experienced endoscopists hamper its application.
However, the cost of biobutanol production via conventional acetone-butanol-ethanol (ABE) fermentation by Clostridium acetobutylicum is not economically competitive, which has hampered its industrial application.
This problem was solved by overexpression of an anti-feedback inhibited NAGK from C. glutamicum ATCC 21831; however, the cost of l-arginine addition and the genetic instability from using a plasmid hampered its industrial application in l-ornithine production.
Although the use of copper as a catalyst was critical for the revolutionary achievement of this cycloaddition reaction, the toxicity of copper has hampered its utility in cellular applications.
Glycosylation analysis provides many opportunities for diagnostics, but its complexity hampers its routine application.
