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However, most hiPSC-derived CMs morphologically and functionally resemble immature rather than adult CMs, which could hamper their application.
However, adverse events in which vector integration activates proto-oncogenes, leading to clonal expansion and leukemogenesis hamper their application.
Adverse events in otherwise successful clinical trials caused by proto-oncogene activation due to vector integration hamper their application.
However, in some instances it is claimed that the low density and low mechanical strength of the macroscopic particles hamper their application.
However, most NIR dyes usually have one or more charge in their structures, which may cause low cell membrane permeability and hamper their application in cell imaging.
However, adverse events in gene therapeutic trials, caused by activation of proto-oncogenes due to murine leukemia virus (MLV -derived vector integration, haMLV -derivedpplication.
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Doctors at all stages have to jump through many evaluation hoops and the competition for training and jobs can be so fierce that they avoid any potential negative factors which might hamper their applications.
However, the high solvent costs of these ionic liquids could hamper their applications at industrial scales.
This accelerates the desiccation and hampers their application as natural hydrogel-like substances.
This low-degradation rate hampers their application in bone repair, which typically has a healing rate of several months.
CNTs are chemically inert and insoluble in the most solvents thus hampering their application and manipulation in various possible fields.
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