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In addition, the number of patients included in this substudy was low, and this may hamper the validity of our results.
This may decrease the ability of the study to generalize the findings to other regions, but should however not hamper the validity of the data.
Moran's I index was computed on the residuals of each ANOVA to test for any possible spatial autocorrelation that could hamper the validity of our inferences.
Population level studies for assessment of magnitude of HIV infection suffer from potential biases, which are likely to hamper the validity and reliability of results [ 20].
15 Such changes clearly hamper the validity of trials, however it is not possible to trace and document if the trials are not registered correctly.
Drugs prescribed in-hospital are not registered on an individual level, which may hamper the validity of register-based studies on drugs potentially administered in-hospital.
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High percentages of missing values on specific items might even indicate that an item is not relevant for the study population, perhaps pointing to ambiguous formulations and hampering the validity of the instruments [ 17, 49].
This might hamper the external validity of our study.
This selection strategy may hamper the external validity of the study.
However, several problems were noted in this paper, which would hamper the review's validity.
While this is very important for methodological and ethical reasons, it has been demonstrated that the use of eligibility criteria may well hamper the generalizability (external validity) of the results [ 1- 6].
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