Sentence examples for hamper the expression of from inspiring English sources

Therefore, the interference of a single protein with chloroplast biogenesis and/or stability of the photosynthetic apparatus might hamper the expression of the remaining ones.

Thus hnRNP C enables exonization of Alu exons to proceed in small steps, without hampering the expression of the primary mRNA isoform.

This data suggests that both the missense and in-frame deletion pore mutations hamper the surface expression of Nav1.7, and may explain the reason for the loss of pain phenotype seen in these patients.

Thirdly, the limited sample size is hampering the expression study.

In addition, the in vitro and in vivo silencing of transgene expression following nonviral transfection has hampered the stable expression of antibiotic genes for selection and specific expression in target tissues.

One of the essential challenges hampering the construction of such systems is the need to precisely optimize protein expression levels for robust operation.

Furthermore, read mis-attribution between recently duplicated genes could hamper the discrimination of expression between close paralogs or alleles.

Therefore we regard this kind of standardisation as mandatory also with larger sample groups to avoid an increase in gene expression variability, which may hamper the detection of minor but still biological significant expressional changes.

Because the C-terminal deletion hampered the ectopic expression, a series of N-terminal deletion mutants of Hsp60c was tested for IKK binding via co-expression with Flag-tagged IKKα in HEK293 cells (Fig. 3C).

Tumour stroma gene expression in biopsy specimens may obscure the expression of tumour parenchyma, hampering the predictive power of microarrays.

Overall, these analyses suggest that the mutations in pol did not hamper the late stages (expression, assembly and budding) of the HIV-1 replication cycle.