Exact(3)
STX3451 selectively kills MPNST-derived cells, but also halts growth of other tumour-derived NF1 cell lines.
It is tempting to propose the existence of a similar epigenetic checkpoint control that senses detrimental alterations in the epigenome and halts growth until these alterations are repaired.
To test this, we treated yeast cells with rapamycin, a pharmacological compound that targets TOR therefore halts growth, and examined the Maf1 protein over time.
Similar(57)
In malignancies, tumor-suppressor genes, which normally restrain cell growth, acquire mutations, from carcinogens like tobacco smoke and radiation exposure, that eliminate the genes' ability to halt growth.
President Bush this year called for voluntary American measures to slow, but not halt, growth in emissions, saying the strict timetables of the treaty would have harmed the economy.
Executives say they have been disappointed too many times by the halting growth of the last year to begin hiring workers in significant numbers.
But we won't make any of those tasks easier by falling into a double-dip recession or enduring months more of halting growth.
Until now, most accounts of this Presidency have been written in a context of halting growth, stubbornly high unemployment, and disaffection on the part of many of Obama's early supporters.
Since the peace conference in November in Annapolis, Md., Mr. Olmert has said that Israel will not halt growth inside the built-up areas of existing settlements that Israel intends to keep in a final peace treaty.
At the local level across much of the nation, efforts to limit sprawl have already picked up strong momentum, with some communities implementing moratoriums on building permits or using other tactics to halt growth.
Rapid growth in China and India has pulled hundreds of millions of people out of poverty, sustained expansion has spread from Asia, where rapid catch-up has a long history, to South America, where halting growth and economic retrenchments were more the norm.
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