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The results show that the clusters of catch bonds feature some hallmarks of cell mechanotransduction in response to the pulling traction.
These are proteins whose amino acid sequences show the structural hallmarks of cell surface receptors but whose triggering molecules are as yet undiscovered.
In addition to the cell migration, our result indicated that Ponatinib could also repress the anchorage-independent growth and colonization, which is also one of the hallmarks of cell transformation.
We set out to see whether known hallmarks of cell cycle regulation occur at the right time in mad2+/− oocytes.
Cell proliferation and migration are hallmarks of cell division.
In addition to outer membrane permeabilization, extensive mitochondrial fragmentation via fission events, together with remodelling of the mitochondrial inner membrane cristae, are hallmarks of cell death [ 32, 33].
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Four hallmarks of cell-signaling networks modularity, redundancy, adaptation, and heterogeneity are offered as support for QL approaches in drug development; in essence, arguing that condensed, nonspecific networks of QL models will capture signaling dynamics although remaining relatively easy to develop.
Molecular hallmarks of cells expressing expanded repeat RNA are nuclear RNA foci of distinct morphology and abundance.
Anchorage-independent growth of cancer cells is a hallmark of cell transformation.
In addition, cell viability was high on PPy(DBS) substrates with few cells showing pyknotic nuclei, a hallmark of cell death (Figure 2C).
Heterogeneity is a hallmark of cell biology, and is strongly evident in primary cell populations isolated from the same tissue [2].
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