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These are hallmark traits of what some experts call psychopathy, a potent blend of antisocial instincts and grandiosity.
The network operational signature transforms genotypic data (i.e., genomic alterations) to regulatory phenotypic profiles (i.e., regulatory logics/strengths), to cellular phenotypic profiles (i.e., hallmark traits) which lead to clinical phenotypic profiles (i.e., a collection of hallmark traits).
'Network operational signatures' which represent gene regulatory logics/strengths enable to quantify state transitions and measures of hallmark traits.
Thus, sets of genomic alterations which are associated with network operational signatures could be linked to the state/measure of hallmark traits.
"At the most basic level benes have two hallmark traits: 1. they are transmitted horizontally and 2. they offer some benefit to their host," says the Santa Fe group.
Inhibiting HSP90 leads to inactivation and proteasomal degradation of multiple oncogenic clients, thereby delivering a simultaneous combinatorial attack on many cancer-causing signaling pathways and on all of the hallmark traits of malignancy.
Similar(40)
Another hallmark trait, his blithe apathy toward the details of governance, also damaged him in California.
The best keyboards in the notebook business; that's the hallmark trait of Lenovo's venerable ThinkPad line that has garnered the brand a strong, loyal following, especially in the enterprise, over the years.
The hallmark trait of being secure with yourself is loving who you are, Bea says.
The hallmark trait of addiction is compulsion and craving: believing that the drug is essential to making your life work, even when it is clearly doing the opposite.
The other hallmark trait of an overachiever is feelings of self-doubt about one's own competence or ability, Arkin says.
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