The understanding of the role of CUB in translational optimization of viral genes has important implications, as CUB may be a hallmark of host virus specificity (Bahir et al. 2009) or virulence (Mueller et al. 2006).
Although diversity in antigen receptor specificities is the hallmark of the adaptive immune system, effective adaptive immune responses are focused in antigen specificity.
Diversity in antigen receptor specificity is the hallmark of the adaptive immune system.
Accumulation of antinuclear autoantibody (ANA) specificities is a hallmark of impending clinical disease.
This is surprising because intrathecal antibody synthesis and oligoclonal IgG of yet unknown specificity are a diagnostic hallmark of MS [ 6].
Elucidation of these mechanisms is essential for understanding the molecular basis of the cell and species specificity which is a hallmark of TCDD toxicity.
Accepting a GI score of >3.0 as the hallmark of active inflammation, the sensitivity, specificity, and accuracy of conventional histology in predicting relapse were 70.6%, 90%, and 79.1%, respectively.
However, none of the current neurotoxin-based models recapitulates the main clinical features of the disease or the pathological hallmarks, such as dopamine (DA) neuron specificity of degeneration and Lewy body formation, which limits the use of these models in PD research.
The hallmark of visual perceptual learning is its specificity for simple visual attributes, frequently being tightly coupled to the trained retinal position [28], [40] [43], orientation [24], [28], [42], spatial frequency [24] and size of a visual pattern [24], [40], [44].
Subtype specificity appears to be a hallmark (and a major hurdle for development) of small molecule fusion inhibitors that target this region of the HA protein.
The diversity of antigen receptors and the specificity it underlies are the hallmarks of the cellular arm of the adaptive immune system.
