Sentence examples for hallmark in the development from inspiring English sources

Also, loss of the epithelial marker E-cadherin is a hallmark in the development of TKI resistance [ 14].

Although the acquisition of genomic alterations has been recognized as a hallmark in the development of cancer, the sequence and role of specific alterations is less clear [ 6].

Myofibroblasts accumulated in clusters (fibroblastic foci) are considered the hallmark cells in the development of lung fibrosis [ 14].

Thus, a growing body of literature suggests that synaptic loss and dysfunction and network disruptions, rather than conventional pathological hallmarks, are main players in the development of cognitive decline in AD.

Angiogenesis, the development of new blood vessels following the proliferation of the endothelial cells of preexisting vessels, is regarded as a hallmark in cancer development 1.

One of the hallmarks in cancer development is the inhibition of apoptosis with a central role of the mitochondria in this process.

The increase of acylglycerols should therefore be considered the hallmark leading to the development of the fatty liver observed in the ob/ob mice [ 42, 43].

Abundant extraneuronal deposit of amyloid-beta (A β) is the major pathological hallmark and plays an early important pathologic role in the development of AD.

Encapsulated within this methodology and these signatures is a vast amount of biological discovery for particular genes implicated in the development and progression of these hallmarks.

Transplantation onto the back of immunocompromised rats consistently resulted in the development of melanoma, displaying the hallmarks of their parental tumors.

The major pathological hallmark of AD plays an early and important pathologic role in the development of AD.