This suggests a non-competitive component of antagonism, or that the half time of 2.3 min for dissociation of MLA is too slow to allow for complete dissociation from the receptor in the timeframe of our measurements [33].
While for insulin internalization Draznin and colleagues [ 41] reported a k = 0.049 min-1 and a half time of 14.5 min, Knuston [ 44] discussed these results informing a k = 0.0023 and a half time of 4.9 hours.
Outdoor air concentrations decreased over time, quickly in an initial phase with a half time of 3.3 hr, and then more slowly over the following 9 days, with an overall half-time of about 2.4 days.
The fluorescent signal in the centre of a particle with a radius of ≈4 µm recovered with a half time of ≈40 s.
RFP611 has an excitation maximum of 559 nm and is 3.6 times brighter than mCherry, although its maturation time is slower at a half time of 1.83 h, and it is slightly less photostable (Kredel et al., 2008).
MBP as the largest diffusion marker did not equilibrate within the time range of the experiments, whereas the 8.5 kDa protein ubiquitin equilibrated with a half time of ≈20 s.
This is comparable to the 83 – 115 nanograms ml-1 peak plasma concentration at 10 – 36 minutes with a clearance half time of 5 – 6 hours after a therapeutic IV dose of 10.6 mg [ 9].
The average half time of Whi5 nuclear entry, which is an estimate of the memory length in the mathematical model (Supplementary file 1A), is 13.7 min in mother cells and 10.6 min in daughter cells, respectively.
This equates to gastric emptying half times of 361 minutes (95% confidence interval 314 to 408 minutes) and 560 minutes (514 to 607 minutes), respectively.
The recovery half times of Nrp1 in the SG state (median = 42 s, n = 4) and in the amyloid-like state (median = 113 s, n = 4) are shown.
Cholesterol in this process turns over with a half time of approximately 24 h [15].
