Half-life densities of mRNAs with low Z scores (< −2) (in black) and the rest of the mRNA population (in red) at different growth rates.
Given the essential dependence of early embryonic cell shape changes and coordinated cell movements on signal transduction pathways, and because receptor density, surface half life and localization is impacted by internalization, it seems likely that endocytosis could be importantly involved in normal embryonic development.
In drug-treated infections, clearance rates significantly correlated with parasite density at the onset of treatment, and this effect was independent of parasite line (parasite half-life ∼ density at day 6 PI; = 5.58, P = 0.03); infections with a higher density cleared at a faster rate and this was controlled for in subsequent analyses.
Once foam generation was complete, properties such as foam height, liquid drainage, half-life, decay time and density were recorded by the dynamic foam analyzer.
Similar results were obtained evaluating the effect of bcl-2 on HIF-1α half-life in high cell density conditions, where the HIF-1α protein half-life was about 20±10 min in control cells, and increased to 40±5 min in bcl-2 transfectants ( Figure S3 ).
Monitoring of drug efficacy therefore relies on calculating the parasite clearance curve in treated infections, with increased infection half-life (time for parasite density to reduce by 50%) taken as a sign of resistance (White 2011).
The still-Life density problem and its generalizations, pages 228-253 in Voronoï's Impact on Modern Science, Book I (P. Engel, H. Syta, eds.; Institute of Math., Kyiv 1998 = Vol.21 of Proc. Inst. Math. Nat. Acad. Sci. Ukraine).
We highlight here three activities of IMD, namely life insurance density (LID), non-life insurance density (NID), and total insurance (both life and non-life) density (TID).
Bococizumab is a humanized monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (prolongsprolongs the half-life of hepatic low-density lipoprotein (LDL) receptors, and reduces circulating atherogenic cholesterol levels.
In fact, we found that bcl-2 overexpression determines an increase of HIF-1α protein half-life also in high cell density conditions, as observed under hypoxia.
There was no evidence that this was due to resource limitation; there was no significant relationship between parasite half-life and red blood cell density.
