Reliability estimations a bit lower were found with regard to the origin scale (r from.73 to.90), especially with regard to the split-half estimation.
Based on the apparent relationships between half-life and these parameters, we propose a procedure of half-life estimation that is a function of age, percent body fat, smoking status, and breast-feeding.
In this study we provide congener-specific reference half-life values for adults and infants and a method of half-life estimation based on individual characteristics.
In this study we reviewed the half-life data in the literature for the 29 dioxin, furan, and polychlorinated biphenyl congeners named in the World Health Organization toxic equivalency factor scheme, with the aim of providing a reference value for the half-life of each congener in the human body and a method of half-life estimation that accounts for an individual's personal characteristics.
Ongoing follow-up will lead to improved half-life estimation.
We support a method of half-life estimation that is a function of age.
We apologize for not explaining this half-life estimation procedure more clearly in the initial submission.
For the half-life estimation of deltamethrin in soil, we followed a first-order degradation model as described by Hill (1983).
For quantitative analysis, the integrated TCDD concentration over time was used as an exposure variable, which was calculated using results from half-life estimation for TCDD and workplace history data.
Further study into the causes of interindividual and intra-individual elimination rate variability, such as the effect of genetic polymorphisms and sensitivity to known factors, would refine half-life estimation accuracy.
Although cross-sectional half-life estimation has been used in an analogous setting for urinary bisphenol A after fasting (Stahlhut et al. 2009), traditional half-life studies follow individuals over time, allowing researchers to compare serum concentration at any point in time with the initial concentration.
