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The trend had substantial implications for many early skyscrapers.
The discovery of proinsulin has also had substantial implications for understanding the physiology of insulin secretion and for clinical medicine.
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Because regional patterns of medical practice are similar for Medicare and non-Medicare patients, the findings have substantial implications for America's health care system.
Their close alliance, unusual between senior party leaders from the House and the Senate, has substantial implications as they head into end-game negotiations with President Obama on the federal budget.
Our results have substantial implications for hydrological measurements made at sandy intertidal sites like Cape Henlopen.
It has substantial implications not only for those directly affected but also for their dependents and society [12, 13].
Educational researchers have paid very little scholarly attention to this economic shift, although it has substantial implications.
Endophthalmitis, an ophthalmic condition characterized by an inflammation of the intraocular cavity, can have substantial implications for vision.
Most obviously the ruling could have substantial implications for search engine Google, whose core business involves hyperlinking to content hosted elsewhere.
The results should have substantial implications to velocity shear layer dynamics involving large density jump, such as planetary magnetospheric boundary layers.
Economic growth, for instance, has long been a top priority for governments, and findings about its impact on human well-being may have substantial implications for policy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com