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He had significant difficulty getting to sleep every night.
After designing the show, the two had significant difficulties getting the series green lit.
Moreover, it has significant difficulties with changing illumination conditions.
If home prices decline 20% over the next several years, a reasonable scenario, then American households will see a $4.2 trillion loss in their net worth and have significant difficulty adjusting to this decline.
As shown in Figure 10, when asked if they encountered difficulties in framework development by applying the F3 approach manually, approximately 52% of the subjects reported having significant difficulty, 29% mentioned partial difficulty and 19% had no difficulty.
Technology has had significant effects on education over the past decade.
Shaikh's mother, who was 19 years younger than his dad, had significant learning difficulties and mental health issues.
Environmental barriers, behavioral difficulties, family functioning/impact and general health had significant associations with psychosocial scores at baseline, but none served as predictors of change over time.
The hospital has had significant changes in leadership as well as financial difficulties in the last decade.
Mr. Cuomo had significant leverage over lawmakers.
They still had significant divergences over the campaign in Afghanistan.
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