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Of 113 patients, 10.6% had significant dehydration.
Twelve patients (10.6%) had significant dehydration, defined as a percentage weight change greater than 5% with rehydration.
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Both the DHAKA Dehydration Score and DHAKA Dehydration Tree had significant AUCs of 0.79 (95% CI = 0.74, 0.84) and 0.76 (95% CI = 0.71, 0.80), respectively, for the diagnosis of severe dehydration.
Additionally, the DHAKA Dehydration Score and DHAKA Dehydration Tree had significant positive likelihood ratios of 2.0 (95% CI = 1.8, 2.3) and 2.5 (95% CI = 2.1, 2.8), respectively, and significant negative likelihood ratios of 0.23 (95% CI = 0.13, 0.40) and 0.28 (95% CI = 0.18, 0.44), respectively, for the diagnosis of severe dehydration.
Gatorade would have significant medical applications for treating dehydration in patients, and has generated over $150 million in royalties for the university and untold millions for its inventors.
Accurate diagnosis of dehydration status in a child with diarrhea has significant consequences both to the individual child and to the health system as a whole.
As such, the initial categorization of the dehydration status of a child with diarrhea has significant consequences, both to the individual child and to the health system as a whole.
CEMOVIS yielded an average inter-membrane distance of 35 nm measured between the centres of electron density, documenting that the plunge-frozen bacteria for the injectisome structure studies had not suffered significant dehydration or changes in buffer osmolarity prior to rapid freezing.
Participants in this study had severe acute watery diarrhea with significant dehydration at presentation, necessitating initial intravenous rehydration.
Although physicians historically have estimated the degree of dehydration based on clinical gestalt, this study confirms the findings of previous evidence that physician gestalt is a poor predictor of significant dehydration in children.
A weight change of ≥5% was considered clinically significant dehydration.
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