Sentence examples for had severe impact from inspiring English sources

Mr. Jordan said Mr. Edwards's "business practices had severe impact on the business climate of the state," scaring away businesses that might have come to the state had their executives not been frightened by a culture of bribes and kickbacks.

42% had no clinical impact, 42% had mild and none had severe impact.

At permissive temperatures, neither the Rpn2 nor the Rpt2 NLS deletion had severe impact on nuclear proteasome localization suggesting a redundancy of proteasomal NLSs (Wendler et al., 2004).

For the past decade, an epidemic called White-Nose Syndrome had had severe impacts on bat populations throughout North America.

Industrialized fishing had severe impacts on species, habitats, and ecosystems [265].

Therefore, unexpected data corruption will have severe impact on future grid operations.

Failure of critical configurations will have severe impact on system reliability and performance.

The space and material budget constraints have severe impact on the design.

These parameters have severe impact on the concentrate and hence project economics.

Adverse events associated with second-line drugs (SLDs) can have severe impact on efficient management.

Hemi-dystonia almost always has severe impact on motor function; however, response to treatment is typically poor [17].