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Meanwhile, Mr Thompson and his colleagues invented ways round numerous technical problems, some of which had never been posed, let alone solved.
The second major breakthrough of the 1930s, the theory of income determination, stemmed primarily from the work of John Maynard Keynes, who asked questions that in some sense had never been posed before.
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Asked directly why the Defense Department can't simply pay for procedures using donor sperm despite state laws, Paul Hutter, general counsel for TRICARE, said, "That exact question that you're asking has never been posed to us for an absolute legal decision".
In the United Kingdom, I had often been asked, "How do you deal with witnessing all the death and suffering in an ETU?" But interestingly, this question has never been posed to me by a healthcare worker or anyone else who lives and works here in west Africa, and it always leaves me stumped.
There had never been such partying, such dressing up, such posing.
Nighy said he had never been a classical English actor, adding that Shakespeare posed a problem "because you can't operate in those kind of trousers".
Booker T. posed the question to Mrs. McKinlay, but she had never been a guest of the President and did not know the answer.
However, the detection of events that are rare or have never been observed poses a challenge for model specification.
The fact that a large fraction of places have never been seen before poses a challenge for the prediction task, since - by construction - any model that attempts to predict a place from an alphabet of previously visited places will be unable to predict new, unseen symbols.
This has never been reported with chemicals and could pose a risk of wrongly evaluating the NMs embryotoxic potential.
Yet he was completely in his own skin off air: if some England skippers have pretended to give the sporting public a sense of the real thing while clinging to the pose, there has never been anything remotely artificial about the hooker from Rotorua.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com