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The very high titers of this wPP-induced serum antibodies alone had modest effect on reducing B. parapertussis numbers (Figure 10B), consistent with prior results with convalescent serum [30], [39].
First, in general, interventions had modest effect on behavior change [ 10, 11, 14, 16].
Interestingly, MEK/1/2 inhibitors AZD6244 or PD98059 had modest effect on E2-enhanced G6PD expression.
Pazopanib and sorafenib had modest effect on GM-CSF driven CFU-GM-CSF drivenwith an IC50 of 1 and 1.7 μ M, respectively.
In contrast, loss of p53 had modest effect on cellular senescence and no effect on macrophage infiltration, but instead allowed maintenance of tumor vasculature, even in regressing tumors.
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Our findings that inhibition of the NOTCH and TLX1 pathways separately had modest effects on leukemia cell growth led us to consider inhibiting these pathways concurrently.
In contrast, the low labeling condition had modest effects on virus activity in the liver and only small effects on viral genomes in the tested organs which did not appear to have perturbed relative distribution.
Spinal manipulation visits had modest effects on cLBP outcomes.
Expression of H2A R11K had modest effects on chromatin de-compaction with marginal statistical significance.
One such mutation, H4 G94P, had modest effects on the interaction between H4 and Asf1.
In vitro, H4G4P had modest effects on nucleosome stability, dramatically reduced histone octamer stability, and altered nucleosome sliding ability.
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