mTOR signalling clearly has essential roles in developing oligodendrocytes and in myelination in the CNS and PNS.
Thus, there is evidence that HS chains have essential functions in development including in ESCs.
However, both enriched IPA pathways in both races have essential roles in asthma pathogenesis [30].
PI3-like kinases have essential functions in checkpoint signal transduction in all eukaryotes.
Lbx genes have essential roles in development, including crucial functions in neural and mesodermal cell specification.
Genes with high transcripts in developing siliques may have essential functions in seed quality and yield.
PcG proteins have essential roles in early development, as well as in ES cells [ 36].
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In vivo studies show that MKK4 and MKK7 have essential roles in embryonic development.
In general such studies implicate that this MTase could have essential functions in bacterial physiology.
