Although cisplatin is not commonly used for the treatment of prostate cancer, we had earlier determined that the combination of docetaxel and phenoxodiol was only additive (unpublished), and we wished to pursue the potentially synergistic combination.
We have earlier determined the structure of Aβ(1 40) in complex with the affibody protein ZAβ3, a selected binding protein based on a three-helix bundle scaffold (Z domain).
The formation constants in this subsystem have earlier been determined and it was found that hydrogen peroxide interacts with vanadate in the whole pH range studied (0.5 10.5).
The presence of CA-125 in ovarian tumor tissue has earlier been determined mainly in a semi-quantitative manner by immunohistochemistry [15].
A smallest region of overlap of deletion has earlier been determined in primary neuroblastomas by our group to an approximately 2 Mbp region between polymorphic markers D1S214 and D1S244 [ 2, 3].
I have written and spoken the words 'one day the diagnosis of Rett Syndrome will be followed by the words "but don't worry, we have a cure for that"' and I myself have had early gender testing in pregnancy to determine whether or not I needed to go on to be tested for Rett (I was having a boy, so I never had to make the decisions which might have followed had it been another girl).
The molecular subtype (luminal A, luminal B, HER2, basal and normal breast-like) for each tumour had been earlier determined by Waddell et al. [ 1].
The circadian clock mutants cca1-11, lhy-21 and cca1-11/lhy-21 [75], [73], [74], [75] have early flowering phenotypes and therefore we determined freezing tolerance of seedlings prior to reproductive growth using two methods.
