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Recruitment began in 1999 and continued until October 2002, when the trial was closed after the announcement that the women's health initiative had been terminated early because the risks of combined HRT seemed to outweigh the benefits in that population.
Conversely, we chose to avoid strategies based on adding a consolidation or a maintenance therapy since two phase III trials had been terminated early on the evidence of futility of treatments and an increase of toxicities.
One explanation could be the existence of labor unions that fight to keep workers employed longer where as many service workers are at will employees and can have jobs terminated earlier during the recession.
The £8m-a-year contract had been terminated four months earlier, amid allegations that the east Belfast firm had overcharged for carrying out work on NIHE properties.
She would have terminated earlier before 23 weeks had she known, however, her doctor is very anti-choice (she was unaware of this) and so her genetic ultrasound occurred late at 21 weeks.
Hibs announced earlier that his contract had been terminated by mutual consent and Morton then revealed he had signed for them until the summer.
A clinical trial using this compound to treat acute migraine has been terminated early due to a lack of efficacy [28].
Even though one antagonist, SB-705498, was shown to suppress and reverse sensitization upon dural inflammation [27], a clinical trial testing the compound in migraine patients has been terminated early due to lack of efficacy [28].
Nine trials have been completed and 5 have been terminated early or withdrawn.
Other trials in patients with sickle cell disease have faced similar issues in recruitment, and many have also terminated early [ 5].
For example, a number of trials in patients with sickle cell disease have been terminated early due to insufficient recruitment [ 5].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com