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Previous studies had demonstrated normal levels of L444P and N370S messenger RNA, with reductions of A120G and P415R mutation bearing messenger RNA in transfected NIH 3T3 cells (Ohashi et al., 1990).
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In selected patients who previously have undergone YAG laser ablation of the endometrium and who have demonstrated normal intrauterine architecture, pregnancy as a planned event may be a reasonable and safe option.
Using cyclin-dependent kinase 2 (CDK2) as a test example, Sperandio et al. have demonstrated normal mode analysis as an effective tool to select relevant target conformations with diverse binding sites (42).
Subsequent studies have demonstrated normal skin sensitivity to electrical stimuli at control points [ 11] or even somatic hyperalgesia with electrical stimuli at active points and areas of pain referral and thermal stimuli on hand and foot.
Numerous studies have demonstrated normal or even supranormal diastolic LV function in athletes ; instead, the pathological forms of LV hypertrophy are typically associated with an impaired diastolic dysfunction characterized by lower early diastolic mitral annulus velocity.
In a previous work, we had demonstrated that normal senescent keratinocytes do not die by apoptosis [4].
From previous studies we had demonstrated a range of normal TERC/ABL expression and showed that patients with DKC1 mutations have significantly lower TERC levels.
Interestingly, STAT3 is not required for the proliferation of normal cells, and multiple studies have demonstrated that normal cells are more tolerant of loss of STAT3 function.
The glucose normalization in ICU patients is a desired goal, as studies have demonstrated that normal glucose levels with low variability (fluctuations) are associated with reduced mortality and less complications in the healing process, compared to hyperglycemic ICU patients [6].
We have demonstrated that normal glial progenitor cell surface markers are widely expressed in glioma cells.
We have demonstrated that normal epithelial cell signatures are predictive of important features of prostate cancer.
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CEO of Professional Science Editing for Scientists @ prosciediting.com