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The Treatment for Adolescents With Depression Study (TADS) was designed to compare the relative and combined effectiveness of cognitive behavior therapy (CBT) and fluoxetine, each of which had demonstrated efficacy in carefully controlled single-site studies.
Partially or non-automated protocols, often instigated by hospital-based quality-improvement teams, also had demonstrated efficacy [ 154- 157].
When bisphosphonates came onto the market, they had demonstrated efficacy in the improvement of bone density, but there was no evidence for reduction of hip fractures.
We could also try sunitinib which had demonstrated efficacy in treating patients with GIST who have experienced disease progression on or intolerance to imatinib [ 6].
A previous study by our group had demonstrated efficacy for SA3N as an in vivo GzmB inhibitor in a murine model of AAA.
Similar(55)
Small trials have demonstrated efficacy in well-defined populations (1).
Therapies directed toward stabilization of mast cells have demonstrated efficacy.
No single intervention has demonstrated efficacy in reducing colorectal SSIs.
Therapies which are directed toward the microbiome such as probiotics have demonstrated efficacy in children with IBS.
With the need for alternatives to pharmacologic agents, vagus nerve stimulation has demonstrated efficacy in treatment-refractory primary headache disorders.
Drugs that primarily target T-cells, like cyclosporine and tacrolimus, have demonstrated efficacy when employed in the treatment of uveitis [9 13].
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