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Similar effects had been observed previously in Gluconobacter oxydans MF1 when the gene coding for glucose dehydrogenase or gluconate-5-dehydrogenase was overexpressed (Merfort et al. 2006).
Such an effect had been postulated previously based on studies in cultured cells [ 15].
Although that fact had been previously established, the effect on performance of the venture had not been.
A similar effect had been previously observed in Hha, when changing the electrostatic balance by the removal of a negative charge via the substitution E53Q, which resulted in complete protein denaturation25.
This effect had been briefly noted previously [ 11].
The effect of age had been previously examined in the HMPS [ 2].
One possible explanation for defects in glucose metabolism could be an inhibitory effect on insulin release as such effects have been reported previously in vitro [ 37].
Several techniques for activating their shape-memory effect have been studied previously and are discussed in this chapter.
While this inhibition effects has been reported previously some unusual behaviour was observed and reported for the first time.
Similar self-controlled current limitation caused by a series resistance effect has been reported previously [25, 34].
Similar effects have been observed previously [12], [26].
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