Since its construction, the canal has been constantly improved; originally 200 feet wide with a maximum depth of 24 feet, it was widened in 1954 to 500 feet at water level and 196 feet at a depth of 33 feet, with the main channel 45 feet deep, enabling ships of a maximum draft of 37 feet to navigate the canal.
The permanent tracking network has been constantly improved and specific campaigns of observations have been conducted in Wettzell, Gads and in Antarctica.
Both approaches use metal cations to bind the negatively charged phosphopeptides, and protocols designed to achieve higher enrichment efficiencies have been constantly improved over the past decade.
This tool has been constantly improved and updated since 2009 and has been used to identify networks associated with cancer metabolism, innate immunity and even complex biofilm communities.
To date, methods are available and have been constantly improved to analyze the dynamics of the proteome, the transcriptome and the metabolome.
Similarly, alignment software suites have been constantly improved over the past few years and several tools are widely used and supported by a large user community.
The performance of OCT has been constantly improved since its introduction, and the latest versions can generate three-dimensional images from multiple A-scans acquired on the optic disc.
They are made using a manufacturing process that has been constantly improving for more than four decades.
To counter the numerous developments in diaphragm cells, chlorine producers who use mercury cells have been constantly improving their techniques towards environmental protection.
Moreover, the accuracy of geodetic measurements has been constantly improving so that in the not too distant future, these "small" GIA contributions may become detectable a clear knowledge of the GIA signal level in these places will help instrument designers target the signal level and accuracies required.
