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By the early 2000s, however, the disparities in VPTB and PTB between Hmong and white women, as well as between Hmong and other Asian women had become substantial.
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Moreover, the biggest Internet start-ups have become substantial companies in their own right.
Some have made money, and a few have become substantial employers, or founded large businesses.
How the book, originally positioned as a first novel with promise, rose to the top of best-seller lists reflects its strength in a wave of literary novels, many of which have become substantial best sellers, including "Atonement" by Ian McEwan (Doubleday) and "The Corrections" by Jonathan Franzen (Farrar, Straus & Giroux).
With the aggressive cost reductions for 3-D printing made available by the open-source self-replicating rapid prototypers (RepRaps) the economic advantage of custom distributed manufacturing has become substantial.
While the proportion of women in taiko has become substantial, some have expressed concern that women still do not perform in the same roles as their male counterparts and that taiko performance continues to be a male-dominated profession.
Workforce shortages have become substantial and are predicted to continue and worsen [ 12].
Recently anti-CCP testing has become substantial part of ACR-EULAR classification criteria for RA [ 6].
However, according to a supply audit by AC Nielsen ORG-MARG Research Ltd., a market research company in India, use of ECPs in large metro cities has become substantial.
He was equally generous with what had become a substantial fortune, donating heavily to Aids research, education and environmental causes.
In 1993, the French photographer Bernard Descamps was organizing an exhibition of African photography in Mali when he approached Fosso, who revealed what by then had become a substantial body of work.
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had become serious
had become crucial
had assumed substantial
had become major
had become enormous
had become large
had become considerable
had become fundamental
had become noticeable
had become great
had begun substantial
had become essential
had been substantial
had contributed substantial
had become equivalent
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CEO of Professional Science Editing for Scientists @ prosciediting.com