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The IR group had a progression risk significantly different from the other 2 groups.
208 patients had a progression of disease (49%).
Radiation therapy was initiated if a patient had a progression disease during the chemotherapy.
Some of the patients may have had a progression rate that was lower than estimated.
Similarly, 50% of probands homozygous for the A allele of rs778294 (M19) had a progression of symptoms.
In the HR group, only 1 patient who had a progression had a follow-up time of less than 2.5 years.
Similar(45)
Median progression-free survival for first-line MP-guided therapy was 8.2 months; 1 patient had a progression-free survival of 49.5+ months.
Of these 66 patients, 27% had a progression-free survival that was longer than expected from their times to disease progression while on previous failed regimens.
In a phase II study of sorafenib in patients with soft tissue sarcoma, patients with angiosarcoma had a progression-free survival of 3.8 months (Maki et al, 2009).
In all, 18 of the 66 evaluable patients (27%) had a progression-free survival (PFS) ratio (PFS on study divided by PFS on prior treatment) of >1.3.
To correlate biomarker changes to the clinical outcome, the patients were categorised into those who had a progression-free survival of <3 months, 3 up to 6 months, or >6 months.
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