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However EDTA had a mild effect in reducing the activity of the GBSV1-NSN enzyme.
In our study, pretreatment with Go6976 (a classical PKC inhibitor) exerted a robust inhibitory effect on nSMase2 induction, whereas Bis pretreatment had a mild effect.
These results indicate that the removal of Limk2 in a colitis-associated CRC mouse model had a mild effect on tumour initiation, but had a significant impact on tumour growth and on the acquisition of a more invasive phenotype.
Of the pharmacological inhibitors of the F-actin cytoskeleton tested, cytochalasin D had by far the strongest effect, whereas jasplakinolide had a mild effect and latrunculin B had none.
We demonstrated that the combination treatment of cetuximab and cisplatin at a low concentration, which had a mild effect on cell growth and apoptosis, significantly potentiated anticancer activities in both cells.
Transgenic expression of markers alone had a mild effect on the habituation defect in rpm-1 mutants because three of four control lines had habituation levels slightly, but significantly, less than non-transgenic rpm-1 mutants.
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The wild type CF2 construct had a milder effect with this driver, resulting in IFM noticeably thinner than wild type, but intact from anterior to posterior, in contrast to the effects of the 88F-GAL4 driver.
Two regions encoded by exon 14 were independently capable of causing a strong exclusion (constructs NFAT51−838 and NFAT5 (1−473) + (839−1377)), whereas the regions encoded by the short exons 13 and 15 had a milder effect (constructs NFAT51−547 and NFAT5 (1−497) + (1378−1455)), and the region encoded by exon 12 did not displace NFAT5 from mitotic chromatin (construct NFAT51−497) (Figure 8).
Depletion of SOCS5 alone had a milder effect.
The deletion of BUD2 had a milder effect (BI = 4.8 ± 1.9).
Compared to WT, drought stress had a milder effect on both the TCA cycle and glycolysis in T2 leaves.
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