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HA act as molecular elicitors of H+ and Ca2+ fluxes, which seem to be upstream of a complex CDPK cell-signaling cascade.
Since the molecular recognition process leads to the adhesion of the host cells and virus, molecules with a high affinity for the viral HA act as potent inhibitors of infection by influenza viruses (Ogata et al. 2007; Schengrund 2003).
Not only does the HA act as a ligand for the target compounds [ 7, 28] but their addition to the water also poses an additional analytical challenge for the determination of the priority pollutants [ 23].
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