Sentence examples for guiding strands from inspiring English sources

In terms of the the 5' terminal nucleotide involved in sorting siRNA and thus guiding strands into AGO complexes, our data revealed no strong bias in siRNAs of BaMV/satBaMV.

The guiding strand assembles into cytoplasmic RNA-induced silencing complex (RISC) with argonaute protein that guides the complex to their complementary mRNA targets [ 15, 16].

Furthermore, expression of some passenger and guide strands of the same miRNA differed during development.

Importantly, guide strands from RNA isolated from mice that had been treated with MTTR-containing plasmids were more easily measurable.

Guide strands were selected for favorable strand biasing, but increased strand biasing did not correlate with potency, suggesting a threshold effect.

We noticed that the 6mer seeds in siL3 and siL2 guide strands have a higher G content than the ones in siL4 and siL1 (Fig. 1b).

One of these proteins, a DNA-cutting enzyme called Cas9, binds to short RNA guide strands that target specific sequences, telling Cas9 where to make its cuts.

Some miRNA* strands might become functional guide strands and they were phylogenetically conserved similar to their mature miRNAs.

For miRNAs, we find this bias for the miRNA passenger strands rather than for the guide strands.

These data support the conclusion that the hairpins generated active guide strands with the mismatch at position 16.

siRNA duplexes with unstable 5′ ends in the guide strands will enable efficient incorporation of the guide strand into the functional RISCs (activated RISCs).