In the latter half of the 20th century, researchers and guidelines organizations began to explicitly challenge the core assumptions underpinning many clinical practices.
Thus to optimize uptake of the guidelines, organizations and practitioners need to be informed about the new guidelines, and given strategies for constructing motivational messages.
Future studies are needed to compare the cost implications of guideline implementation across settings and among different types of guidelines Organizations in this evaluation study volunteered to participate and are therefore a self-selected group.
This interface was selected because it is commonly available in medical institutions and guideline organizations [ 35].
For educational resources and guideline organizations, selections were not mutually exclusive.
These guideline organizations use the internationally developed AGREE instrument for testing the quality of the guidelines they produce [ 28].
The filter can be useful to anyone seeking sex-specific clinical evidence (e.g., guideline organizations, researchers, medical educators, clinicians).
The Dutch network of guideline organizations adopted the AGREE Instrument, and reached consensus in methods for assessing and synthesizing the evidence [ 8, 9].
Guideline organizations, including NCCN and ASCO, have advised targeting BRCA1 and BRCA2 testing to probands whose probability of mutation carriage is approximately 10% or greater.
Firstly, we selected 56 guidelines from a larger set of clinical guidelines published by four guideline organizations: the Dutch College of General Practitioners (NHG), the Dutch Institute for Healthcare Improvement (CBO), the Scottish Intercollegiate Guidelines Network (SIGN) and the National Institute for Health and Clinical Excellence (NICE, United Kingdom).
Although the filter has been developed for guideline organizations, it has also potential relevance to a much wider spectrum of users of clinical evidence, e.g. researchers, medical educators and practitioners.
