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Despite these guidelines, it seems the government too often relinquishes the burden of proof when conducting its strikes, especially when using what are called "signature strikes"—where drone operators target the suspicious behavior of any "military-aged males" in designated areas, such as Waziristan in Pakistan and Abyan Province in Yemen.
Without clear guidelines, it seems difficult to create a stable scientific system fed by basic and applied research that could lead to economic growth in the country.
Second, when developing guidelines, it seems sensible to take the required time investment of recommendations into account, since this may affect the likelihood that recommendations are followed.
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On the contrary, due to the lack of evidence based guidelines, it seemed that clinicians preferred to err on the side of overtreatment in node negative patients who entered the control arm.
While this study showed improved adherence to a specific set of clinical guidelines (IMCI) it seems likely that this same result could be achieved with the use of electronic guidelines in other areas such as maternal health, chronic illness and infectious disease where national guidelines are often available but used sporadically.
10 In any guideline elaboration, it seems important to base treatment decisions on biological age and not chronological age; we are not equal in terms of aging – physiological, social, and cognitive changes can appear and they are specific to each individual.
Given this and the non-significant differences in iCAHE scores found between the three testers (moderate to excellent agreement for 17 of the 18 guideline assessments), it seems that the iCAHE instrument could be applied by anyone, with no prior experience or training.
Given these challenges and the different emphases in guidelines it therefore seems quite possible that different actors tackling the same research question but in different contexts might come up with very different conclusions with regard to benefits, beneficiaries, and obligations and thus very different perspectives on the social value of their research.
In fact, the DEA once set guidelines to help physicians understand what practices would keep them safe from arrest before withdrawing the guidelines when it seemed like they might be used as a legal defense.
Until there are clear evidence-based guidelines, it would seem prudent to treat SAM and acute medical problems with initiation of ART once the child is stabilised.
However, although from the ABCDE bundle or PAD guidelines it may seem evident what to aim for in everyday clinical practice, health care professionals often struggle with how to implement guidelines, especially when these include integrated care covering many domains concurrently and involving multiple care providers.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com