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Up to 94% of variation in the quality score among guidelines could be explained by the quality of evidence used for guidelines development.
The low quality of most guidelines could be explained by the fact that the AGREE instrument was not used by the committees that were developing or updating the guidelines.
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The rather high baseline levels of awareness and use of guidelines (in both groups), also likely contributors to the modest effects on guideline use, could be explained by how the survey questions were phrased and the availability of other guidelines.
It is most likely that the positive effect of the guidelines on disease-free survival could be explained by this practice.
This result could be explained because CEIPC guidelines were widely disseminated to all kind of centers, regardless their academic characteristics.
We suggest that the differences could be explained by the history of guideline development in Norway and Denmark respectively.
The mismatch among providers on the instructions given to caretakers could be explained by the failure to adapt and translate the WHO treatment guidelines into the national treatment guidelines.
The persistence of screening urinalysis use – in nearly a quarter of all child visits - could be explained by a physician lack of awareness of the AAP guideline [ 1– 3].
The improved care could be explained by increased focus on diabetes as a modern epidemic, increased professional knowledge about clinical guidelines, increased patient knowledge, and the coverage of diabetes in mass media.
Patient-level predictors of diabetes preventive services, such as age or chronic condition, could be explained by physician practices, in response to patient health-related behaviors and the U.S. Preventive Task Force USPSTFF) guidelines (16, 17).
This could be explained by travel motives.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com