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Specialists additionally feel that guidelines cause an increase in workload, there is no adequate financial compensation, and there is a shortage of the necessary personnel [ 22].
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Dementia in these patients is not necessarily defined with international criteria and Dutch consensus guidelines, causing a risk of bias.
We tested whether the prescribed dosage regimen of nadroparin, according to Dutch guidelines, causes accumulation of nadroparin.
Finally, the standard cryoprecipitate dose recommended in most guidelines causes a modest increase in plasma fibrinogen levels in bleeding trauma patients.
(Health post, Hill, Key informant interview) In some cases, it was not clear whether the lack of clarity in the guidelines caused the (unintentional) misuse of funds, or if they were wilfully misused.
Night float systems alternate at weekly intervals as per the ACGME guidelines, causing not only a disruption in one's internal balance but creating a cycle where a resident may not have sufficient time to recover from the disruption before being exposed again to a 12-hour shift.
These guidelines have caused a shift from an exercise-fitness paradigm to a physical activity-health paradigm[ 8].
Geographic and socioeconomic differences in investigation and treatment have been reported for patients with cancers of the breast [ 30, 31, 32] and variations in investigation or departure from treatment guidelines have caused inequity in survival [ 24, 33, 34].
The IEGMP conducted a wide-ranging inquiry including consultation with the public and on 11 May 2000 issued the "Stewart Report" (after the surname of its chairman), which concluded that "the balance of evidence to date suggests that exposures to RF radiation below NRPB [National Radiological Protection Board] and ICNIRP guidelines do not cause adverse health effects to the general population".
Most of all we hope that, in combination with related initiatives, the TOP guidelines will cause future generations to look on the term "open science" as a tautology – a throwback from an era before science woke up.
And a 1998 article in JAMA, the Journal of the American Medical Association, warned that failure to strictly follow the guidelines could cause poisonings "even in countries where quality control procedures are usually strictly applied".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com