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Nevertheless, we consider the rationale to be stronger for ROTEM ®-guided, concentrate-based therapy.
Analysis of transfusion requirements of packed red blood cells (PRBC), plasma (FFP), platelet concentrates and the usage of fibrinogen and prothrombin complex concentrate (PCC) in ICU patients before and after the introduction of thromboelastometry guided factor concentrate based coagulation algorithm for the treatment of coagulopathy in massive bleeding and its influence on cost of therapy.
Retrospective analysis of the utilisation of blood products (PRBC,FFP, platelet concentrates in therapeutic doses) and fibrinogen and PCC before and after the introduction of thromboelastometry guided factor concentrate based coagulation algorithm.
The usage of all allogenic blood products has decreased in our unit after the introduction of thromboelastometry guided factor concentrate based coagulation algorithm by 46,7%.
We have achieved a major reduction in allogenic blood products after the introduction of a thromboelastometry guided factor concentrate based coagulation algorithm in our intensive care unit.
Implementation of thromboelastometry guided factor concentrate based coagulation algorithm reduces the exposure of intensive care patients to allogenic blood products and does not increase cost of therapy of bleeding and coagulopathy.
The usage of thromboelastometry has been increasing since 2009 and in January 2014 we have implemented POC thromboelastometry guided factor concentrate based coagulation algorithm for the treatment of coagulopathy in massive bleeding [1].
Furthermore, researchers should be guided to concentrate on future research that ultimately will help guide practice.
Nevertheless, FIBTEM appears to be a valuable means of guiding fibrinogen concentrate therapy in the perioperative setting.
In addition, a favourable survival rate was observed in patients administered with fibrinogen concentrate with or without prothrombin complex concentrate guided by ROTEM.
The dosing of fibrinogen concentrate was guided by FIBTEM thromboelastometry.
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