Sentence examples for guided alignment from inspiring English sources

Sequences shorter than 100 amino acids were omitted from analyses as those tended to align poorly even in a guided alignment (data not shown).

This could affect alignment slightly, in the case of non-annotation guided alignment, for a small number of ambiguously aligning reads.

CoMFA and CoMSIA analyses were done using ligand based and receptor guided alignment schemes.

By providing a causal framework for proposing molecular homology, secondary structure consensus guided alignment contrasts with the methods that rely on simple sequence similarity or congruence optimization.

Reference guided alignment to both mouse and rat reference genomes and consensus sequence assembly was performed with MAQ 0.7.1 [ 22] using default settings.

First, since automated methods, like RNASalsa [ 89], remain largely underappreciated, secondary structure guided alignment still relies on extremely time-consuming manual alignment.

Thus, quality assessment of data via e.g. secondary structure guided alignments, discarding of randomly similar aligned positions or heterogeneity of the data set prior to analysis is a crucial step to obtain reliable results.

Images were deconvolved, projected and manually aligned as layers in Photoshop, using GFP filaments and follicle cell nuclei in overlapping regions to guide alignment.

The insert sizes were checked by digestion with EcoRI, sequenced by Sanger sequencing, and assembled using Sequencher 4.10.1 using non-repetitive flanking sequences to guide alignment.

Although the approach varies, each of these methods aligns read data to guide alignments using reference trees to determine the best homology.

DIALIGN is based on a segment-to-segment comparison [ 22, 23], while ALIGN-M uses a non-progressive local approach to guide alignments [ 24].