Sentence examples for guide the selectivity from inspiring English sources

These observations collectively suggest that the direct binding of photosensitizers to specific proteins may guide the selectivity of protein modification in PDT-treated cells.

This interesting selectivity profile may guide the design of new, specific inhibitors of target mammalian aminopeptidases with one active site zinc.

These mechanistic insights provide critical information to guide the design of catalysts with tunable selectivity for CO2 reduction by H2 at atmospheric pressure.

It is expected that simulations can guide the design of water purification membranes with both high selectivity and high permeability.

The selectivity profile of these new, low molecular weight structures may guide the design of specific, non-peptidic inhibitors of binuclear aminopeptidases.

Comparing at high-throughput 3-D features of protein cavities is likely to play an increasing role to guide the functional annotation of novel genomic structures as well as predicting target-based selectivity profiles for pharmacological ligands.

The results indicate that site-directed mutagenesis, guided by the selectivity-conferring code of NRPSs A domains, represents a powerful alternative for the genetic manipulation of NRPS biosynthetic templates and the rational design of novel peptide antibiotics.

Second-site binders were identified during the NMR-based screen, guiding the synthesis of bidentate compounds with increased affinity and selectivity.

The results provide the tools for predicting the affinity of related compounds, and for guiding the design and synthesis of new ligands with predetermined affinities and selectivity.

Guiding the Guides, by Ingela Björck, 27 June 2003.

Moreover, discrete residues in the IDH1 allosteric pocket that differ from IDH2 may also guide IDH1 isoform selectivity.