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Our in vitro and in silico study offered a significant framework toward the understanding of risk assessment of BZTs and provides guide for future design of environmental benign BZTs-related materials.
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Therefore, the validation of various turbulence models is of great importance to the process of ensuring that the numerical results are trustworthy and that they serve as a guide for future designs.
But that absolutist approach also entails unexpected sacrifices in other aspects of life, particularly when avoidance of failure and accident becomes the guiding principle for future design and behavior.
Our risk stratification approach has potential implications for diagnosis, for guiding therapy and for future design of clinical trials in patients with acute respiratory distress syndrome (ARDS).
The findings of these molecular modeling studies can serve as a useful guide for future rational design of potential agents with better antihypertensive activity.
The preferred range was a highly populated narrow band covering 50% of the approved drugs, which would be used as a directional guide for future compound design by moving the property closer to this range.
It provides a fundamental understanding of the water transport through the Aquaporin-embedded vesicular biomimetic membrane which is a critical guide for future biomimetic membrane design and performance enhancement.
These findings provide a critical guide for future rational drug design of DMXAA variants with potential IFN-β-stimulating activity in humans, which are needed for the development of anticancer therapies and vaccine adjuvants.
Three-dimensional quantitative structure activity relationship (3D QSAR) studies were performed using Comparative Molecular Field (CoMFA) and Comparative Molecular Similarity Indices Analyses (CoMSIA) to better understand the structural basis for biological activity and guide the future design of more potent VE analogues.
The novel mass-transport mechanism obtained in current study may provide a theoretical foundation for guiding the future design of graphene membranes with outstanding separation performance.
These findings reported in this work are expected to guide the future design of advanced electrode systems for efficient hydrogen evolution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com