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Netrins are important in axonal guidance, regulation and maintenance of central nervous system and are also involved in the development of mammary gland, lung, pancreas, and blood vessel [23].
The Biological Process GO terms include axon guidance, regulation of response to stimulus, regulation of neuron differentiation and behavior, among many others.
We found that networks related to pathways involved in axon guidance, regulation of synaptic transmission, and regulation of transmission of nerve impulse are overrepresented.
Consistent with known functions of previously identified genes that are required for radial migration, the functions of the 18 SVZ-IZ specific NEUROD2 targets converged on axon guidance, regulation of neuronal polarity and actin cytoskeleton (Additional file 7) [ 1].
Finally, by applying formal network analysis, we will show that these apparently unrelated genes are overrepresented by statistically significant gene ontology (GO) networks related to pathways such as those that involve axon guidance, regulation of synaptic transmission, and regulation of transmission of nerve impulse.
In their data, upregulated genes identified between P3-PCs and P7-PCs were enriched for pathways such as "axon guidance", "regulation of actin cytoskeleton", "gap junction", and "tight junctions", implicating roles for these genes in the early stages of circuit integration by PCs.
Similar(52)
Not later than 120 days after December 21, 2000, the Assistant Attorney General and the Federal Trade Commission shall issue or amend their respective industry guidance, regulations, operating manuals and relevant policy documents, to the extent appropriate, to implement each reform in this subparagraph.
If the FDA imposes tissue guidance regulations on surrogacy, it will impact the ability of couples from Europe and gay couples internationally and domestically to utilize the services of a gestational carrier in the United States.
As we introduce national entitlements to core services, we will do away with detailed guidance and regulation.
The coalition government has, since 2010, significantly reduced the burden of statutory guidance and regulation upon local authorities, something which has been broadly welcomed across the sector.
An increase in the number of affordable drones on the market has seen rapid adoption by the public with little to no guidance or regulation.
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