Sentence examples for gs pathway from inspiring English sources

Moreover, they showed very different antagonist potencies that could be exploited to study the activation of the Gs pathway, with or without concomitant block of Gq/11 signaling.

Interestingly, this RASSL showed no evidence of constitutive signaling via the Gi or Gs pathway.

Negative feedback processes regulate the Gs pathway in order to prevent excessive cell signalling.

Harrison and colleagues demonstrated a role for the host erythrocyte stimulatory G protein (Gs) pathway in erythrocyte invasion [3].

Having previously demonstrated a role for the G-alpha-s gene, GNAS, in severe malaria disease, we sought to identify other important components of the Gs pathway.

First, it is exclusively coupled to Gs at physiologically relevant concentrations of agonist [19], thus the effects of receptor activation can be clearly attributed to the Gs pathway.

Further Gs pathways involved in P. falciparum infection of erythrocytes are not upregulated in orthochromatic cells, and it should be noted that pathways can be targeted without eliciting a transcriptional response.

These results suggest that Cerulenin triggers apoptosis, at least in part, via a caspase-independent AIF/Endo G pathway, with only modest activation of caspase -8,-9,-3 and PARP.

Moreover, our results suggest that continuous exposure of arterial SMCs to NO in fact up-regulates RGS5 expression via the soluble guanylyl cyclase/protein kinase G pathway.

The AIF/Endo G pathway is a major caspase-independent apoptotic cascade (Daugas et al, 2000; Ahn et al, 2004; Cande et al, 2004; Cregan et al, 2004).

Mitochondria-dependent caspase pathway as well as AIF and Endo G pathways is also found to contribute to the induction of apoptosis by baicalein [ 41].