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In concordance, recent functional studies pointed to an essential role of GRP in zebrafish skeletal development and calcification [ 5], albeit GRP-deficient mice did not reveal evident phenotypic alterations in skeletal architecture, development, or calcification [ 6].
Little SAAS is colocalized with GRP in ∼4× more neurons than with VIP, despite VIP-positive neurons being >2× more abundant than GRP-expressing cells.
However, the physiological role of GRP in cardioventilatory regulation is incompletely understood since most functional studies have been carried out using bombesin rather than GRP.
The two-dimensional high-order extension is constructed employing the generalized Riemann problem (GRP) in the acoustic approximation.
Figures 6 and 7 present the results for the key links based on their influence on real GRP in the different Egyptian macroregions.
One common feature is that, for all governorates, better access to markets generates higher GRP in the context of our simulations.
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In this first study about GRPs in – to our knowledge – the largest series of human esophageal adenocarcinomas so far, we aimed to investigate GRP expression in tumors without disturbing influences of cytotoxic treatment as it strongly may influence the expression of GRPs.
It has also been appeared that most of the GRPs in tumor cells is engaged in multi-chaperone complexes, while it is not in normal cells [41].
Indeed, frog GRPs in which PCP is perturbed by knockdown or overexpression of Vangl2 show substantially less posterior bias of cilia positioning, and these embryos fail to correctly lateralize.
The greater diversity of GRPs in this species may reflect a form of antigenic variation.
Moreover, we observed a group of glycine-rich RNA-binding proteins (GRPs) in this category.
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