Severe form is characterized by intrauterine growth retardation, severe growth failure after birth, recurrent infections, hematological abnormalities, hypothyroidism, cerebrovascular disease and often death within the first 15-years.
Moreover, the ups and downs of the European economy — the distance it travels between strong growth and severe downturns — have been less than in the United States in recent decades.
Though known for sunny days and verdant farms -- particularly now, as thousands of acres of fruit orchards burst into bloom -- the valley suffers from both sprawling growth and severe smog, almost as bad as Los Angeles's.
Forced overexpression of miR-101 significantly inhibited cholangiocarcinoma growth in severe combined immunodeficiency mice.
These can include smaller head or brain size, poorly formed eyes, slow growth and severe learning difficulties.
Nontransformants exhibited reduced growth and severe leaf chlorosis caused by Fe deficiency, whereas the gNAAT lines had greener and larger shoots.
Forced overexpression of miR-34a in CCA cells inhibited their proliferation and clonogenic capacity in vitro, and suppressed tumor xenograft growth in severe combined immunodeficiency mice.
Dicke's discovery saved millions of children and adults from the perils of untreated celiac disease, including malnutrition, stunted growth, cancer, severe neurological and psychiatric illness and even death.
